Four Suffolk County, N.Y. mosquitos and two dead birds tested positive for West Nile virus.
No humans have contracted the virus so far, and officials plan on working to keep the virus contained, The Wall Street Journal reported.
Officials have asked local residents to eliminate any stagnant water near their homes, because this is where the infected pests breed.
Many counties around the U.S. have been spraying to keep mosquitos at bay, but other areas are trying a more natural approach.
In Plano, Texas, they are introducing an army of mosquito-larvae loving fish into the environment, the Dallas News reported.
"They will eat other things, but if there's mosquito larvae, they will tend to pick that over anything else," Joseph Daley, Plano's stormwater program administrator, said. "So it's kind of like eating your dessert - for them, anyway."
The "mosquitofish," are part of an effort to battle nature with nature.
"Other fish that eat insects may take mosquito larvae, but the advantage of the [Gambusia affinis] is their mouthparts are directed upwards so they are able to take the larvae at the surface of the water, so they are very effective predators of that kind of insect," Dr. James Kennedy, regents' professor of biology at the University of North Texas, said.
About 70 percent of humans don't experience any symptoms after contracting the mosquito-borne illness, the Centers for Disease Control and Prevention reported.
About one in five people who get bit by the infected mosquitos will develop headache, body aches, joint pains, vomiting, diarrhea, or rash. Most people with this type of the virus, called Febrile illness, will recover completely.
Around one percent of the infected get more serious symptoms including: headache, high fever, neck stiffness, disorientation, coma, tremors, seizures, or paralysis
There is no vaccine for the virus, people with serious symptoms are hospitalized and given "intravenous fluids, pain medication, and nursing care."
West Nile has already infected humans in: Arizona, California, Colorado, Iowa, Mississippi, Nebraska, Nevada, South Dakota, Tennessee, and Texas.
Cases have been found in these states, but no infections have been reported in humans: Connecticut, District of Columbia, Florida, Idaho, Illinois, Indiana, Louisiana, Massachusetts, Michigan, Minnesota, New Jersey, Ohio, Oregon, Pennsylvania, Utah, Washington, West Virginia, Wisconsin, Wyoming, and now New York.