Young girls who received the human papillomavirus (HPV) vaccine are as likely as unvaccinated girls in the chances of getting pregnant, contracting sexually transmitted infections, or going for contraceptive counselling, reveals a new study by Kaiser Permanente Center for Health Research and Emory University in Atlanta.
The study rejects parental fear that the vaccination against the human papillomavirus will encourage teen sex. The research paper published online in the journal Pediatrics reveals that since the introduction of HPV vaccine known as Gardasil, there have been concerns - raised both in peer-reviewed literature and the popular media - that use of the vaccine might lead to increased sexual activity, due in part to the mistaken belief that Gardasil protects against pregnancy and sexually transmitted diseases other than HPV. However, this independent research project says there is no evidence to support these concerns.
"Our study found a very similar rate of testing, diagnosis and counseling among girls who received the vaccine and girls who did not," said Robert Bednarczyk , PhD, an epidemiologist and the study's lead author. "We saw no increase in pregnancies, sexually transmitted infections or birth control counseling - all of which suggest the HPV vaccine does not have an impact on increased sexual activity."
Since 2006, the Centers for Disease Control and Prevention recommended girls between the ages of 11-12 receive three doses of the vaccine to protect them from HPV, which is transmitted through sexual activity and can cause genital warts and cervical, penile, vaginal, and head and neck cancers. The vaccine is also recommended for females ages 13-26 who did not receive the vaccine when they were younger, and for males ages 11-21.
The study included 1,398 girls ages 11-12 who were members of the Kaiser Permanente health plan in Georgia in 2006 and 2007, during the first 18 months after the Gardasil vaccine became available.
Of this group, 493 girls received at least one dose of the HPV vaccine during the study period. The comparison group included 905 girls who received other recommended vaccines but not the HPV vaccine. Researchers followed both groups of girls for up to three years to assess whether they had been tested for or diagnosed with a sexually transmitted infection (STI), had taken a pregnancy test, and had been counseled about contraceptives.
About 10 percent of the girls in the study, both those who received the vaccine and those who did not, had one or more of these outcomes. The average age of testing, diagnosis, or counseling was about 14.5. Only eight girls, or less than 1 percent, were diagnosed with an STI or had a positive pregnancy test. Girls who received the HPV vaccine did not have a statistically higher rate of testing, diagnosis, or counseling compared to those who did not receive the vaccine.
"This is reassuring news for teenagers, parents, and members of the public," Robert Davis , MD, MPH, a co-author and senior investigator with the Kaiser Permanente Center for Health Research-Southeast said. "Our study adds to growing evidence that the HPV vaccine is a safe and effective way to prevent these rare but sometimes deadly cancers."