Judd Apatow fired away at Bill Cosby and the venues still hosting his stand-up gigs on his Twitter this past weekend.

Apatow opened up the lively debate on Friday evening by tweeting at the Centre in the Square in Kitchener, Ontario and asking if the venue would really allow Cosby to perform on their stage next month. The comedian faces nearly two-dozen accusations of rape over the last 50 years.

He also addressed his question to Budweiser Gardens in London, Ontario, which plans to host Cosby the next night.

Apatow did retweet a story on the Centre in the Square's website about why the venue had not cancelled Cosby's performance. The venue explains the event is a rental show and only the "external promoter" can cancel the Cosby gig.

"Commercial rental shows at The Centre are crucial for the venue to earn sufficient funds to operate. This show was contracted over a year ago with tickets on sale for a number of months. While we may personally share concerns raised by the community, if The Centre forces a cancellation of this rental show it isn't simply a situation of giving back the rent," the Centre wrote.

The Centre would be contractually obligated to pay back all the tickets sold, Cosby's guaranteed fee, and the promoter for "any losses from box office and show expenses."

Mere minutes into his Twitter discussion, Apatow began to receive replies from other users defending Cosby. The "Knocked Up" director didn't back down and responded to the fans that refuse to believe the number of women who continue to step forward since Hannibal Buress put Cosby back under the microscope following an October stand-up performance.

He picked up his tweeting the next day to defend the accusers who run the risk of others not taking their claims seriously.

Apatow also gave the spotlight to a couple Twitter users with very few followers whose logic he strongly disagreed with.

By Sunday, Apatow had had enough with the Twitterverse and packed it in.