With the recent casting of Tom Holland, Marvel and Sony Studios' new "Spider-Man" reboot is well underway. Holland will make his Marvel Cinematic Universe debut as the wall-crawler in next year's "Captain America: Civil War" before getting his own solo flick in 2017.

But with five big screen Spider-Man films to date, how will Marvel go about differentiating this new version? For starters, the Big Bad may be someone fans aren't familiar with at the moment.

"Right now we're interested in seeing villains we haven't seen before," Marvel head honcho Kevin Feige told Birth Movie Death. That's especially interesting considering the recent rumors that suggested Matthew McConaughey was up for the role of Norman Osborn. But if Feige can be believed, the first new "Spider-Man" film will not feature the Green Goblin, Venom, Sandman, or Elektro.

Beyond Spidey's opposition, Feige is hoping to strike a new tone with his rebooted Spider-Man.

"It's the soap opera in high school, and those supporting characters, that are interesting," Feige said. "Just as we hadn't seen a heist movie in a long time, or a shrinking movie in a long time, we haven't seen a John Hughes movie in a long time. Not that we can make a John Hughes movie - only John Hughes could - but we're inspired by him, and merging that with the superhero genre in a way we haven't done before excites us."

Hughes is famous for his comedic yet emotional films about coming of age. His notable work includes "Ferris Bueller's Day Off" and "The Breakfast club."