The "Full House" spinoff will have to explain at least one absence when Netflix revives the ABC sitcom.

Mary-Kate and Ashley Olsen have declined the invitation to reprise their role as Michelle Tanner in the new Netflix series, "Fuller House," according to The Hollywood Reporter. The twin sisters have decided to focus on their business ventures, but still support the show.

"Although Ashley and Mary-Kate will not be a part of 'Fuller House,' I know how much 'Full House' has meant to them and they are still very much considered family," executive producer Robert L. Boyett said in a statement to The Hollywood Reporter. "It has been exciting to see how they have built their professional careers, and I support their choice to focus on their fashion brands and various business endeavors. I appreciate their support and good wishes towards 'Fuller House.'"

The Olsen twins have not acted over the last five years. Ashley last appeared on screen in 2010's "I'm Still Here" in an uncredited role and Mary-Kate has not starred in anything since 2011's "Beastly."

"Fuller House" will revolve around the recently widowed D.J. (Candace Cameron-Bure) who has two children and another one on the way. She asks her best friend Kimmy (Andrea Barber), who also has a teenage daughter, and sister Stephanie (Jodie Sweetin) to move in with her to help take care of her growing family.

Other original cast members that have officially signed on to the spinoff include Dave Coulier as Joey and John Stamos as Uncle Jesse. The latter will also serve as an executive producer on the show.

Bob Saget and Lori Loughlin are still in negotiations to return as Danny Tanner and Rebecca Donaldson-Katsopolis, respectively.

Production will start soon on "Fuller House." Netflix has not announced a premiere date.