Obviously, it has managed to inspire quite a range of reactions on the social web.
Just last week, Clinton, a possible 2016 presidential candidate and early favorite to win the Democratic nomination, was the subject of Times magazine's cover with the headline, "Can anyone stop Hillary?" accompanying it.
Sending the Twittersphere into a tizzy and meme production into overdrive, the Times magazine's odd approach to depict the former first lady and secretary of state as a planet proved to be a success, Yahoo News reported.
"Is this a joke?" Politico's Ben White tweeted. "Nope," the Times' David Joachim replied. "No joke. That's the cover."
To be published on Sunday, the Times' Arem Duplessis explained the thought process behind the cover in a blog post, Yahoo News reported.
"When we created the cover of this Sunday's magazine to accompany Amy Chozick's article about Hillary Rodham Clinton's influence on the various people within her political universe, the immediate idea that came to mind was Clinton's face embedded on a planet similar to the man-in-the-moon image from the 1902 silent film 'Le Voyage Dans la Lune,'" Duplessis said.
"It's as if Yes and David Lynch did quaaludes and had a lovechild," The Blaze's Becket Adams tweeted.
The image of Clinton was likened to a "Conehead" by The National Review's Johah Goldberg, according to Yahoo News.
Chris Carlon tweeted an image of Miley Cyrus swinging on top of Planet Clinton as it serves as the pop star's personal "Wrecking Ball."
The Atlantic Wire produced Hillary Bieber, a mashup of Planet Clinton and Justin Bieber's mugshot released on Thursday by police in Miami, Yahoo News reported.
"This has the benefit of mashing up with today's other major meme," the Atlantic wrote. "Two memes! No waiting!"
"If this is an indicator of the bizarre shenanigans in store for the 2016 election cycle, then we're pretty excited," Time's Samantha Grossman wrote. "Very, very confused, but also excited."