From NASA:

"Ground controllers have maneuvered the space station's large robotic arm Canadarm2 in place for work planned for Wednesday's spacewalk. Spacewalkers Barry Wilmore and Terry Virts will start their second spacewalk at 7:10 a.m. EST to lay more cables and lubricate one of Canadarm2's two latching end effectors, which serve as tip or base for the robotic arm. They will also prepare the Tranquility module for the relocation of the Permanent Multipurpose Module and the new Bigelow Expanded Activity Module later this year."

American astronauts Barry Wilmore and Terry Virts spent Tuesday preparing for Wednesday's spacewalks while Italian astronaut Samantha Cristoforetti did some "high-flying plumbing," according to NASA. Cristoforetti also participated in the "Drain Brain" experiment that studies how blood flows from the brain to the heart in microgravity.

The Russian cosmonauts took a day off on Tuesday in observation of the Russian Defender of the Fatherland holiday.

Spacewalk coverage begins at 6 a.m. EST.

Broadcast live streaming video on Ustream

HNGN's coverage of the first spacewalk can be seen here.