Prominent Staten Island, N.Y.-based hip-hop group Wu Tang Clan once issued a warning with its 1993 hit "Wu-Tang Ain't Nuthing Ta F' Wit," but pharmaceutical industry villain Martin Shkreli must not have gotten the message. After a Twitter feud erupted between Shkreli and Wu-Tang Clan rapper Ghostface Killah last week, the notorious "Pharma Bro" threatened the hip-hop artist in a new video message.

"Dennis, I'm gonna call you by your government name," Shkreli said in the video clip obtained by TMZ. "You're not a Ghostface Killah. Sorry."

Flanked by three masked cronies, Shkreli warned Ghostface that it's not OK to "beef" with him. He insulted the rapper and accused him of being an "old man who's trying to reclaim the spotlight." Shkreli continued to threaten Ghostface and said if the rapper continued his "beef," then Shkreli would erase Ghostface's voice from the sole copy of Wu-Tang's latest album, "Once Upon a Time in Shaolin."

Shkreli became the owner of the one-of-a-kind album when he bid $2 million for the record last year, as previously reported by HNGN. He was notoriously dubbed "Pharma Bro" after he purchased rights to the cancer and AIDS drug Daraprim, raising the price from $13.50 to $750 per pill.

The "beef" started on Twitter last week when Ghostface called Shkreli a "shithead" in a video interview with TMZ and criticized Shkreli's price gouging. Shkreli responded with a jab at Ghostface's album sales via Twitter and Ghostface responded in another TMZ video, where he called Shkreli, "The Michael Jackson nose kid."

"A @GhostfaceKillah response tomorrow evening," Shkreli posted on Twitter after the release of his video message. "Don't cry, Ghost. All rap careers come to an eventual end. Long time coming, motherf--ker."

Watch Shkreli's full video response below.