Republican front-runner Donald Trump has blamed former secretary of state and 2016 Democratic leader Hillary Clinton for the deaths of "hundreds of thousands" of people who have been killed in the Syrian civil war and by ISIS.

"She is the one that caused all this problem with her stupid policies," Trump said in an interview on Fox News Sunday with Chris Wallace. "You look at what she did with Libya, what she did with Syria. Look at Egypt, what happened with Egypt, a total mess. They don't back — we don't back any of our allies. You look, she was truly, if not 'the,' one of the worst secretary of states in the history of the country. She talks about me being dangerous. She's killed hundreds of thousands of people with her stupidity."

"What do you mean, hundreds of thousands?" Wallace responded.

"She was secretary of state. Obama was president, the team," said Trump. "Two real geniuses."

The Syrian Observatory for Human Rights said earlier this year that more than 300,000 Syrians have been killed since the five-year civil war, CNN reported.

Trump also used the opportunity to criticize Clinton on her handling of the attacks on the American consulate in Benghazi.

"Look at Benghazi, our ambassador," he said. "He wired her five or six hundred times asking for help. She'll take her friend's call every time. Hillary Clinton doesn't have the judgment. She doesn't have the strength or the stamina to be president. She will be a terrible president. And I think I'll win."

Clinton said earlier this week that Trump's proposal to temporarily ban Muslims from entering the U.S. was "dangerous."

"He has gone way over the line. And what he’s saying now is not only shameful and wrong, it’s dangerous,” Clinton said, according to Business Insider.

The former secretary of state said Trump's proposal "plays right into the hands of terrorists" by alienating Muslims in Western countries and framing terrorism as a clash between Islam and the West.

“I don’t say that lightly, but it does. He is giving them a great propaganda tool, a way to recruit more folks from Europe and the United States," said Clinton. "And because it’s kind of crossed that line, I think everybody and especially other Republicans need to stand up and say, ‘Enough. You've gone too far.'"