YouTube sensation-turned-reality star Whitney Thore is gearing up for ups and downs in season two of her hit TLC series "My Big Fat Fabulous Life," People reported. Thore moves out of her parents' house and into a new home with potential love interest Buddy Bell, embarks on a new health and fitness journey and makes milestones in her career as an activist for body positivity in the preview clip for the upcoming season.

"Moving out of my parents' house is closing one chapter and starting another," she says in the clip. But moving in with Bell, whom she admitted to having dated in the past in an episode from the previous season, complicates their friendship.

"There's about to be some temptation up in that new house," her friend teases.

Thore received a health scare last season when her doctor informed her that she was pre-diabetic, and this season shows her making changes to her exercise and eating habits. She attends underwater exercise classes and attempts to run a 5k, but she's shown stopping to gag before she can reach the finish line.

However, Thore also takes steps in her role as an activist for body positivity with her "No Body Shame" campaign, and she gives a tearful inspirational speech after performing a dance routine at a baseball field in her hometown of Greensboro, N.C.

"I hope that you take this experience and you can apply it to the rest of your life and realize it's never too late to do what you love," she says.

Watch the full preview clip below and be sure to catch the season two premiere of "My Big Fat Fabulous Life" on Wednesday, Sept. 9 at 9 p.m. ET on TLC.