A powerful storm system that hit a large portion of the greater Texas region and affected areas from Mexico to Oklahoma this past weekend has left at least 22 people dead.

Two people in Houston were killed in flash floods that terrorized the city on Monday night, according to The Houston Chronicle. The first victim was found at 5 a.m. on Tuesday in a flooded pickup truck, while the other was discovered floating in a bayou.

The city was hit with more than 11 inches of rain between Monday and Tuesday, CNN reports.

Houston, and the area in general, is known to have flash flood warnings, but according to Mashable, as recent as three weeks ago the region was still in the midst of a drought that began in the state back in 2010. That drought, as well as one in Oklahoma, are now over.

More than 1,000 homes were damaged or destroyed because of the weather, according to the Associated Press.

"You cannot candy coat it. It's absolutely massive," Texas Gov. Greg Abbott said of the destruction while declaring 37 of the state's counties as disaster zones.

The death toll is expected to rise as people across the region remain missing. In Hill County, Texas, 12 people's whereabouts are still unknown; eight of them were vacationing near the Blanco River, which surged well above flood stage, according to CNN.

Ciudad Acuña took the brunt of the storm in Mexico. Thirteen people were killed when a tornado swept through the city that borders Texas.

Below is a video YouTube user Bryan Rumbaugh filmed of the destruction in Houston. He used a drone to get a bird's eye view of the area.

Weather maps showed that the storm was going to cripple the region. The National Weather Service said on Tuesday that warnings in Texas were still active until noon local time.

Other residents of areas hit by the storm took to social media to chronicle its aftermath.

Heading for higher ground #Austinflood A video posted by JwGriggs (@jwgriggs) on May 25, 2015 at 5:03pm PDT

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