Tishomingo County lost a Mississippi Bureau of Narcotics agent during a shootout with a suspect early Saturday. Three other officers are in a hospital, wounded, according to USA Today.

Lee Tartt, 44, was killed in the line of duty while responding to a domestic situation in a local residence. The incident started around 5:15 p.m. EST. The residence in question was that of a man named Charles Lee Lambert. He was inside his home with his wife and a 10-year-old daughter when the officers arrived. The situation escalated to a stand-off when the man refused to comply with officers' instructions to come out of the residence, according to FOX News.

Lambert, 45, was also killed during the incident, while the wife and the daughter were rescued and unharmed.

The three other officers remain hospitalized, two of the officers have non-fatal wounds while the condition of the third wounded officer remains unknown, Fox News added.

"Our men and women in law enforcement put themselves in harm's way every hour of every shift. This is a tragic reminder that their willingness to serve can exact the highest price," said Phil Bryant, Mississippi governor, as he relayed his condolences and asked residents to pray for the late officer's family, according to Reuters.

The Mississippi Bureau of Narcotics has not had an agent killed in the line of duty since 1998.